Published 14 February 2012
OncoPep has signed an exclusive, worldwide license agreement with Dana-Farber Cancer Institute for a multi-peptide therapeutic cancer vaccine technology.
Financial terms of the agreement have not been disclosed.
PVX-410, the first vaccine developed from this technology, is designed to target multiple myeloma cells.
A Phase 1/2a trial, in which PVX-410 will be studied in patients with smoldering multiple myeloma, is planned for 2012.
PVX-410 is composed of four proprietary, synthetic peptides to form a therapeutic cancer vaccine, which is designed to target specific antigens found on the surface of multiple myeloma cells.
PVX-410 has demonstrated the ability to stimulate a strong immune response against multiple myeloma cell lines and patient cells in vitro.
OncoPep CEO Doris Peterkin said the license with Dana-Farber provides them with an underlying technology that will give the company the opportunity to develop additional therapeutic vaccine candidates in the future.
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